Stroke work-up

Screening tests

Serum glucose, electrolytes, calcium/phosphorus, magnesium, uric acid, liver and thyroid function tests

Lipid profile (cholesterol, triglycerides, LDL-cholesterol)

INR, APTT,PTT

CBC, ESR, CRP

RPR, TPHA

ECG, EEG

Transthoracic or esophageal echocardiogram

Doppler carotid and vertebral arteries

Brain CT or MRI scan, MRA/MRV

Specific investigations

Blood/serum

ANA, ACE, antiphospholipid antibodies, anticardiolipin antibodies, lupus anticoagulant

Protein/immunoelectrophoresis

Screening sympathomimetic drugs (amphetamine, cocaine)

Lactate (mitochondrial disorders)

Protein C and S, antithrombin III, Factor V Leiden (if patient on warfarin/heparin), APCR

Serum homocysteine, urine homocysturia

Factor V Cambridge

Beta2-glycoprotein antibody screening

Euglobulin clot lysis time

Miscellaneous

Carotid and vertebral angiography

Genetic testing

Prothrombin G20210A mutation

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